Cellular & Molecular Biology
Researchers in the IBMS Cellular & Molecular Biology cluster use multifaceted experimental approaches to understand the molecular mechanisms of biological processes and their contribution to the function of cells, tissues, and organisms. Ongoing research ranges from investigations of fundamental molecular processes - such as regulation of gene expression, intracellular trafficking, cellular homeostasis, and cell division - to studies of cellular differentiation and the development of complex, multicellular biological structures. Students in the cluster will gain an appreciation of the molecular and cellular underpinnings of biological form and function.
Image: Deconvolution microscopy of mitotic cells showing the spindle assembly checkpoint. Image courtesy of the laboratory of Kevin Vaughan.
Contact
Laurie Littlepage (website>)
Department of Chemistry & Biochemistry
Contact by email
(574) 631-4804
Participating Faculty
Francis J. CastellinoChemistry and Biochemistry |
In vitro and in vivo relationships between hemostasis and inflammation |
Patricia A. ChampionBiological Sciences |
Molecular genetics of mycobacterial protein secretion and pathogenesis |
Patricia L. ClarkChemistry and Biochemistry |
Protein biophysics in living cells |
Karen Cowden DahlBiochemistry & Molecular Biology (IUSM-SB) and Chemistry and Biochemistry (ND) |
Ovarian cancer metastasis |
Crislyn D'Souza-SchoreyBiological Sciences |
Signal integration and cancer progression |
Ana Lidia Flores-MirelesBiological Sciences |
Molecular, Cellular, and Immunological Analysis of the Pathogenesis of Catheter-associated Infections |
Holly GoodsonChemistry and Biochemistry; Biological Sciences |
Molecular and cell biology and biophysics |
Kasturi HaldarBiological Sciences |
Understanding disease pathology and developing treatments in rare and neglected diseases |
Paul W. HuberChemistry and Biochemistry |
RNA expression, processing, and localization |
David R. HydeBiological Sciences |
Visual System Development and Dysfunction |
Shaun LeeBiological Sciences |
Molecular microbiology and biosynthesis of peptide antibiotics |
Laurie LittlepageChemistry and Biochemistry |
Modeling cancer progression in vivo to develop biomarkers and therapies; contributions of the microenvironment to breast and prostate cancers
|
Xin LuBiological Sciences |
Molecular Understanding and Immunotherapy of Metastatic Cancer; Novel Animal Models for Rare Cancers |
Mary Ann McDowellBiological Sciences |
Immunoparasitology |
Joseph O'TousaBiological Sciences |
Photoreceptor function and processes of retinal degeneration |
Athanasia PanopoulosBiological Sciences |
Somatic cell reprogramming; cancer therapeutics and regenerative medicine |
Jeni ProsperiBiochemistry and Molecular Biology (IUSM-SB) and Biological Sciences (ND) |
Breast cancer biology and chemotherapeutic resistance |
Felipe H Santiago-TiradoBiological Sciences |
Cryptococcal cell biology and host interactions important for disease
|
Zachary SchaferBiological Sciences |
Cancer cell biology and metabolism |
Molly Duman ScheelMedical and Molecular Genetics (IUSM-SB) and Biological Sciences (ND) |
Genetic and comparative analysis of invasive cellular growth; vector mosquito developmental genetics |
Jeff SchoreyBiological Sciences |
Immunology and Cell Biology of Mycobacterium - Host Cell Interactions |
Margaret SchwarzPediatrics (IUSM-SB) and Chemistry and Biochemistry (ND) |
Anti-angiogenic factors in lung and tumor development |
David SeversonBiological Sciences |
Mosquito Genetics and Genomics |
Joshua ShroutCivil & Environmental Engineering & Earth Sciences; Biological Sciences |
Bacterial biofilms, cell-cell signaling, and surface motility |
Cody J. SmithBiological Sciences |
Development and Regeneration of the Nervous System |
Sharon StackChemistry and Biochemistry |
Proteolysis and adhesion in cancer metastasis |
Richard TaylorChemistry and Biochemistry |
Synthetic organic chemistry; polyketide natural products as chemotherapeutic agents |
Kevin VaughanBiological Sciences |
Molecular basis of organelle transport |
Katharine WhiteChemistry and Biochemistry |
Cellular pH dynamics; pH-sensitive mechanisms regulating proteins, pathways, and cancer cell behaviors |
Rebecca WingertBiological Sciences |
Developmental biology and regeneration |
Siyuan ZhangBiological Sciences |
The role of tumor microenvironment in drug resistance and tumor metastasis |