A genetic vulnerability in clear cell renal cell carcinoma, the most aggressive type of kidney cancer, may lend itself to a combination treatment strategy that causes the cancer cells to self-destruct, according to recent research in PNAS.…

While most believe artificial intelligence is changing science, researchers at the University of Notre Dame are exploring the reverse.

Relying on a urinary catheter is a standard part of medical care for hundreds of thousands of patients each year. Unfortunately, the device carries the risk of catheter-associated urinary infections (CAUTIs), where bacteria are widely recognized as the primary cause. And yet, many patients…

Researchers at the University of Notre Dame and collaborators have disclosed the core assembly of the germinosome, which is alarm system that awakens the dormant spores of Clostridioides difficile (C. diff), a health threat that causes about half a million infections and about 30,000 deaths a year.…

Five researchers at the University of Notre Dame earned a Faculty Early Career Development Program Award (CAREER), the most prestigious award from the National Science Foundation (NSF) for early-career faculty. Those who win CAREER…

Stained lung tissue showing tumor reduction with use of TICTACs…

In a study published in Nature Communications, Saurja DasGupta, a biochemist at the University of Notre Dame, and colleagues present a key mechanism for sustaining RNA-based life: an engineered enzyme that selectively recognizes and repairs broken RNA.

The protein PA2854 (shown in red) in Pseudomonas aeruginosa links the outer-membrane protein OprI (shown in blue) to the cell wall (depicted in white), a process that is necessary for the health of the bacterium. (Graphic provided by the Mobashery Lab) Researchers at the University of Notre Dame and collaborators...

Researchers from the University of Notre Dame have published the first known detailed study of breast cancer tissue from Native American women. The study, published in npj Precision Oncology, reveals important molecular differences that may impact the efficacy of therapies for female, Native American breast cancer patients.

  More than 1 million people in the U.S. live with multiple sclerosis (MS), a disease that damages the brain, optic nerves and spinal cord by attacking myelin, the protective coating around nerve cells. Katrina Adams and her research team at the University of Notre Dame are studying how myelin...

Douglas and Diana Berthiaume have made a transformational gift to the University of Notre Dame to advance biomedical research through strategic investments in critical infrastructure. The gift, totaling $35 million, establishes the Center for Biomedical Discovery. It includes $5 million in seed funding for multidisciplinary research teams, promoting new collaborations...

Steve Corcelli, Ph.D., William K. Warren Foundation Dean of the College of Science, has announced the college’s faculty award recipients for the 2025–26 academic year. Father James L. Shilts, C.S.C./Doris and Gene Leonard Teaching Award Bestowed annually on a faculty member…

When Notre Dame students go to access their course materials online, it’s highly likely their instructor is sharing them through the Canvas learning management system. The Canvas Legends Awards, sponsored by the Office of Information Technology’s Teaching & Learning Technologies team, place the spotlight on faculty turning that seemingly routine...

On Tuesday, March 24, University leaders, faculty members, and community partners gathered in downtown South Bend to celebrate research and innovation at the 1st Source Faculty Commercialization Award dinner. This event honors faculty researchers at the University of Notre Dame and Indiana University…

Four teams of researchers across the College of Science and the College of Engineering have been selected to receive seed funding from the Notre Dame Sensor Initiative (NDSI) for research advancing affordable, fast, and accurate platforms for on-site…

To invade healthy tissues and continue growing, aggressive cancers mimic and circumvent the body’s native piping system of veins and arteries. Through this process, known as vasculogenic mimicry (VM), tumor cells form fluid-conducting channels that transport blood, oxygen, and nutrients directly to…

Steven A. Corcelli, professor of chemistry and biochemistry at the University of Notre Dame, has been appointed the William K. Warren Foundation Dean of the College of Science by University President Rev. Robert A. Dowd, C.S.C., effective April 1. Corcelli, who has served as interim science dean since July, was...

Motivated by the experience of caring for two children with a rare disease, Dave and Cathleen Reisenauer have made a transformative gift to the University of Notre Dame to establish a rare disease institute within the College of Science — allowing the University to build on its legacy and leadership...

Internationally recognized biomedical engineer John Fisher will join the University of Notre Dame as director of the campus-wide Bioengineering & Life Sciences Initiative (BELS) and Arthur J. Schmitt Professor in the Department of Aerospace and Mechanical Engineering. His appointment begins Aug. 1. Fisher is currently chair of the Fischell Department...

Patricia Champion, Notre Dame Collegiate Professor in the Department of Biological Sciences at the University of Notre Dame, has been elected as one of 63 Fellows of the American Academy of Microbiology…