All are invited to attend the free Cancer Wellness Symposium via Zoom on Tuesday, September 22. 

Frank Doyle: The Control of Time A challenging problem in systems biology is to rapidly re-entrain circadian oscillations that have been forced out of synchrony with the environment due to external factors such as jet lag or shift work. Recent studies have identified small-molecule pharmaceuticals which effect dose-dependent changes in the mammalian circadian clock, providing an avenue for control of circadian amplitude and phase. In this work, we use a molecular model of the mammalian circadian gene regulatory network to inform a model predictive controller (MPC) for optimal re-entrainment of the circadian clock. Practical constraints on the re-entrainment process arise...

Patricia Champion, Associate Professor, Department of Biological Sciences, Notre Dame, will give a seminar entitled "Conserved mechanisms of mycobacterial disease" on Tuesday, September 22nd at 4:00 p.m.   Join Zoom Meeting https://notredame.zoom.us/j/97418951441…

Mary Ann McDowell, Associate Professor, Department of Biological Sciences, Notre Dame, will give a seminar entitled "Attacking the Complexity of Vector-borne Diseases" on Tuesday, September 29th at 4:00 p.m.   Join Zoom Meeting https://notredame.zoom.us/j/97794004070…