Drugs to treat cancer and Alzheimer’s disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting of surface-accessible “pockets” with a specific, well-defined structure. Traditional drug design involves finding small molecules with shapes that...

Mr. Mike Harper, benefactor of the Harper Cancer Research Institute (HCRI), died this weekend in Omaha NE at the age of 88. 

Professors of chemistry and biochemistry, Paul Helquist and Olaf Wiest, together with Frederick Maxfield of Cornell University have received a U.S. patent for potential treatments for Niemann-Pick Type C (NPC) disease. Patent No. 9,333,222, “Histone deacetylase inhibitors as therapeutic agents for Niemann-Pick Type C Disease,” covers the full class of...

2016 Midwest Ovarian Cancer Coalition Workshop Highlights Research, Treatment and Advocacy   Over 70 researchers from a dozen universities in the Midwest gathered at Notre Dame for the 3rd Midwest Ovarian Cancer Coalition (MWOCC)* workshop to discuss the latest advances in ovarian cancer research.  With a welcome from Mr. Gene Pranzo,...

Notre Dame Research will be participating in the Alumni Association’s Annual Reunion event on the first Friday of June on the third floor of the Main Building. From 9 a.m. to 12 p.m., the dome will be open to tours, where several offices will open their doors to alumni, faculty,...

For Ruth Hillebrand, compassionate health care was both a professional and personal mission. A clinical psychologist in Manhattan, she specialized in treating patients with eating disorders. She also had an intimate knowledge of how compassion on the part of a physician could impact a patient’s treatment and recovery. A physician...

A new cancer fighting technology developed by Basar Bilgicer and Tanyel Kiziltepe, two professors with deep ties to the University of Notre Dame’s Advanced Diagnostics & Therapeutics (AD&T) initiative, is making a rapid and exciting transition to a real-world, commercialized product—one that could increase the effectiveness of cancer medications while...

The Indiana Clinical and Translational Sciences Institute (CTSI) awarded pre-doctoral training, post-doctoral training, and young investigator awards in translational research to four Notre Dame researchers. The training awards provide funding for research that is translational in nature, taking advantage of the clinical collaboration.

The Indiana Clinical and Translational Sciences Institute (ICTSI) recently announced its 2016-17 TL1 Postdoctoral Training Award recipients.   ICTSI was able to fund 5 postdoctoral awards (2 renewals and 3 new awards) this period.  The awards, funded by ICTSI (partially funded by the National Institutes of Health, National Center for Advancing...

2016-17 CTSI Young Investigator Training Awards The Indiana Clinical and Translational Sciences Institute (ICTSI) recently announced its 2016-17 Young Investigator Training Award recipients.  ICTSI was able to fund 10 Young Investigator Awards (4 renewals and 6 new awards) this period.  The awards, funded by ICTSI (partially funded by the National...

Researchers Marya Lieberman and Neil Lobo have received two of the first ever pilot project awards. Read more: http://ctsi.nd.edu/news/66768-indiana-ctsi-global-health-pilot-project-grants-awarded-to-notre-dame-faculty/.

A novel three-dimensional cell culture technique is making it possible for researchers to study tumors and evaluate potential cancer therapeutics quicker and more efficiently. 

New research from the University of Notre Dame will be used to generate maps that provide time-sensitive, mosquito-to-human ratios that determine patterns of mosquito population dynamics for the Zika virus. The model outputs will be available online to provide users with the ability to find reported cases and estimated incidences...

Building on the partnership that the University of Notre Dame formed with the Ara Parseghian Medical Research Foundation in 2010, the University has now established the Ara Parseghian Medical Research Fund and is moving the administrative functions and granting process of the foundation from Tucson, Arizona, to Notre Dame. Through...

Onthis World Ovarian Cancer Day (May 8), we want survivors to know that dedicated  ovarian cancer researchers  are gathering on May 21&22 at the University of Notre Dame  to share their research findings about ovarian cancer biology.  We  want to build on our basic knowledge and use it to provide women with better treatments...

"There were only four surgeons participating in the tissue bank when I was hired. Now we have eighteen. My job is not only to protect the patients but get more surgeons on board. I had to knock down many doors which takes time and patience” says Page-Mayberry. One of the...

Cancer Research:  “no form of wisdom can be left out”   Following the news this spring, it has been gratifying to see the international spotlight turned repeatedly on cancer research.  President Obama’s announcement of a “moonshot” program to cure cancer provides new…

The Indiana Clinical and Translational Sciences Institute (CTSI) has provided support for Olaf Wiest, University of Notre Dame professor of chemistry and biochemistry, and Robert Stahelin, Indiana University School of Medicine associate professor of biochemistry and molecular biology and adjunct associate professor of chemistry and biochemistry at Notre Dame, through...

Nearly 70 percent of ovarian cancer cases are detected after metastasis, which is the development of secondary malignant growths distant from the primary site of cancer. Understanding ovarian cancer metastasis is a research focus of M. Sharon Stack, the Ann F. Dunne & Elizabeth Riley Director of the Harper Cancer...

Graduating Biology major, Diane Choi, is being honored with multiple academic achievement awards as the Class of 2016 prepares for graduation. Choi is the recipient of three major undergraduate awards for her work while a science student at Notre Dame.   The awards include the Outstanding Biology Student Leader Award from...