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Controlling gene expression to halt cancer growth

Author: Paul Murphy

NUT midline carcinoma (NMC) is a cancer without a cure, and one that affects all age groups. NMC is a rapid-growth disease with an average survival time of four and a half months after diagnosis, making the development of clinical trials for potential therapies or cures for this cancer difficult,...

Notre Dame researchers make neurological disease breakthrough

Author: William G. Gilroy

Results of a study by a group of University of Notre Dame researchers represent a promising step on the road to developing new drugs for a variety of neurological diseases. The group from the University’s Departments of Chemistry and Biochemistry and Biological Sciences and the Freimann Life Sciences Center focused...

Two biology faculty receive NIH director’s New Innovator Award

Author: Julie Hail Flory

Shaun Lee and Rebecca Wingert, assistant professors in the Department of Biological Sciences at the University of Notre Dame, have been selected as recipients of the highly competitive National Institutes of Health (NIH) director’s New Innovator Award. Each award covers $1.5 million in research expenditures over five years. The award,...

Mass spectrometry and imaging facilities enable cancer cell discovery

Author: Paul Murphy

A breakthrough in the laboratory of Kevin Vaughan, associate professor of biological sciences at the University of Notre Dame, will assist researchers in understanding cell cycle regulation. The group identified a novel protein that is regulated by the mitotic kinase Aurora B, an important factor in mitosis, or cell division....

Notre Dame research reveals brain network connections

Author: Marissa Gebhard

Research conducted by Maria Ercsey-Ravasz and Zoltan Toroczkai of the University of Notre Dame’s Interdisciplinary Center for Network Science and Applications (iCeNSA), along with the Department of Physics and a group of neuroanatomists in France, has revealed previously unknown information about the primate brain. The researchers published an article in...

Researchers discover protein dynamics help regulate cell division

Author: Marissa Gebhard

A collaborative study between the laboratories of Jeff Peng at the University of Notre Dame and Felicia Etzkorn at Virginia Tech has discovered an important element of how an enzyme involved in cell division does its job. Their report, “Stereospecific gating of functional motions in Pin1,” was recently published in...

Science dean to embark on second ride for rare disease research

Author: Julie Hail Flory

Gregory P. Crawford, dean of the College of Science at the University of Notre Dame, and his wife, Renate, will for the second consecutive year set out on a remarkable bicycle ride this summer to support research seeking treatments and a cure for Niemann-Pick Type C (NPC), a rare and...

Notre Dame chemist sheds new light on antibiotics and the survival of bacteria

Author: Julie Hail Flory

Research in the laboratory of Shahriar Mobashery in the University of Notre Dame’s Department of Chemistry and Biochemistry has led to further understanding of how a bacterial cell wall cross-links, an event that penicillin and other antibiotics disrupt, a step in the maturation of a cell wall that is critical...

Breakthrough in Niemann-Pick Type C research reported by Notre Dame and Cornell scientists

Author: William G. Gilroy

A paper announcing a breakthrough discovery in the fight against Niemann-Pick Type C, coauthored by Olaf Wiest and Paul Helquist of the University of Notre Dame’s Department Chemistry and Biochemistry and Frederick Maxfield, Chair of Biochemistry at Cornell University Weill College of Medicine, appears in the Proceedings of the National...

Malcolm Fraser elected fellow of American Academy of Microbiology

Author: William G. Gilroy

Malcolm J. Fraser Jr., professor of biological sciences at the University of Notre Dame, has been elected a fellow of the American Academy of Microbiology, an honorary leadership group within the American Society for Microbiology. The election recognizes Fraser’s long record of teaching and innovative research, especially in the fields...