Notre Dame physicists investigate plasma tool for destroying cancer cells Notre Dame researchers led by Sylwia…

University of Notre Dame biologists Nicole Achee and Neil Lobo are leaders of an international $23 million research grant from the Bill & Melinda Gates Foundation. Their five-year project will generate the data required to show the effectiveness of a new paradigm in mosquito control — spatial repellency — for...

The William K. Warren Foundation of Tulsa, Okla., has made a $3.5 million gift to the University of Notre Dame that, combined with a previous gift valued at $6.5 million, will endow the creation of The Warren Family Research Center for Drug Discovery and Development in the College of Science....

A new research paper from the labs of University of Notre Dame researchers Holly Goodson and Mark Alber helps resolve an ongoing debate about the assembly of a subcellular network that plays a critical role in cell function and disease.

Standing at a microscope in her Harper Hall laboratory, Karen Cowden Dahl, adjunct assistant professor of chemistry and biochemistry at the University of Notre Dame and assistant professor of biochemistry and molecular biology at the Indiana University School of Medicine-South Bend, is scanning through a petri dish filled with cancer...

The University of Notre Dame and Loyola University Chicago are joining forces in a multidisciplinary cancer research collaboration. The goal of the alliance is to provide direct support for revolutionary new cancer research, with the ultimate objective of making cancer a more manageable, and potentially curable, disease.

Irregular expressions of a panel of regulatory microRNAs (miRNA) in blood and other physiological fluids may allow early screening of many kinds of cancer. However,  the current technologies for identifying and quantifying small numbers of these short (22 bases) molecules in physiological samples require expensive instrumentation and extensive personnel. These...

Cancer’s origin point—a human gene gone haywire—is, in many cases, also its weak spot. If you could block the abnormal function of a gene that is important for metastasis, the theory goes, then maybe you can stop cancer from spreading. But there’s a catch—hit the weak spot with too much...

University of Notre Dame researchers have, for the first time, identified the enzymes that are detrimental to diabetic wound healing and those that are beneficial to repair the wound. There are currently no therapeutics for diabetic wound healing. The current standard of care is palliative to keep the wound clean...

A paper published in a special edition of the journal Science proposes a novel understanding of brain architecture using a network representation of connections within the primate cortex. Zoltán Toroczkai, professor of physics at the University of Notre Dame and co-director of the Interdisciplinary Center for Network Science and Applications,...

The Indiana Clinical and Translational Sciences Institute, which includes the University of Notre Dame as a member, has received a nearly $30 million grant from the National Institutes of Health (NIH) to continue its mission of accelerating research discoveries across Indiana and beyond.

  Dr. Jenifer Prosperi, a researcher at the Harper Cancer Research Institute, is studying how to treat breast cancers that evolve when a crucial tumor suppressor gene goes silent. Over the past 15 years, the scientific community has come to understand…

New research published in the journal Nature Chemical Biology shows that a group of scientists, led by faculty at the University of Notre Dame, has made concrete progress toward the development of the first-ever inhibitory therapeutic for type-I hypersensitive allergic reactions.

  University of Notre Dame researchers Shahriar Mobashery and Mayland Chang and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics. The work, published in the Proceedings of...

At the Harper Cancer Research Institute, Dr. Karen Cowden Dahl is leading research on ARID3B, a mysterious gene that could hold promise for identifying more aggressive forms of ovarian cancer. Standing at a microscope in her Harper Hall laboratory, Dr. Karen Cowden Dahl is scanning…

A new paper by Zoltán Toroczkai, professor of physics and concurrent professor of computer science and engineering at the University of Notre Dame, and his collaborators provides a predictive model of cerebral cortical connectivity at the interareal level. The study was published in the Oct. 2 issue of the journal...

Imagine your children, your nieces, nephews, or grandchildren losing a parent to cancer. Too many experiences and dreams are ripped away due to this terrible disease. But with new, more effective cancer treatments being developed, the prognosis for cancer patients is improving little by little. …

Imagine your children, your nieces, nephews, or grandchildren losing a parent to cancer. Too many experiences and dreams are ripped away due to this terrible disease. But with new, more effective cancer treatments being developed, the prognosis for cancer patients is improving little by little. …

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function. Obesity and diabetes have...

Patricia L. Clark, the Rev. John Cardinal O’Hara, C.S.C. Professor of Chemistry and Biochemistry, has received a $3.8M award from the National Institutes of Health (NIH) to lead a pioneering model of collaboration that draws together seven institutions, eight co-PIs and six postdoctoral associates to study macromolecular interactions in living...