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Notre Dame-Bruker partnership promotes advancements in imaging

Author: Marissa Gebhard

The University of Notre Dame has established a formal partnership with Bruker Corp., a world leader in scientific instrumentation. The partnership will develop one of the Midwest’s top imaging facilities at Notre Dame. The arrangement, called Bruker at Notre Dame (BAND), will allow the Notre Dame Integrated Imaging Facility (NDIIF)...

Notre Dame researchers offer new insights on cancer cell signaling

Author: William G. Gilroy

A pair of studies by a team of University of Notre Dame researchers led by Crislyn D’Souza-Schorey, professor of biological sciences, sheds light on a biological process that is activated across a vast range of malignancies. Wnt proteins are a large family of proteins that activate signaling pathways (a set...

Notre Dame and Harper researchers developing novel method to test for HPV and oral cancers

Author: William G. Gilroy

Research being carried out at the University of Notre Dame and its affiliated Harper Cancer Research Institute (HCRI) may lead to the development of a rapid, cost-effective means of screening for oral cancers and the human papillomavirus. M. Sharon Stack, Ann F. Dunne and Elizabeth Riley Director of the HCRI...

New paper offers insights into how cancer cells avoid cell death

Author: William G. Gilroy

  A new study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. The findings may reveal a novel chemotherapeutic approach to prevent the spread of cancers. Metastasis, the spread of...

2nd Annual Research Day

Author: Angela Cavalieri

Dr. Anil K. Sood, Professor of Gynecologic Oncology and Cancer Biology at the MD Anderson Cancer Center, was the Keynote Speaker to a capacity crowd in Raclin-Carmichael Hall at the Second Annual HCRI Research Day on April 15. 

Brian Baker named an associate editor for Journal of Immunology

Author: Stephanie Healey

Brian Baker, associate professor of chemistry and biochemistry, has been selected as an associate editor for Journal of Immunology.  The journal publishes peer-reviewed articles in all areas of experimental immunology, which includes both basic and clinical studies. All editors of the bi-monthly journal are practicing scientists and the publication is...

Notre Dame imaging specialists create 3-D images to aid surgeons

Author: Marissa Gebhard and Gene Stowe

Watch Video University of Notre Dame researchers have successfully created three-dimensional anatomical models from CT scans using 3-D printing technology, a process that holds promise for medical professionals and their patients. A paper by the researchers, “3D Printing of Preclinical X-ray Computed Tomographic Data Sets,” was published in the Journal...

Designing more effective cancer treatments

Author: Arnie Phifer

A potential landmark paper by Notre Dame researchers could help identify and adjust important parameters for designing targeted nanoparticle-based cancer treatments for years to come. At the same time, the results of the study shed light on a decades-long debate among cancer researchers.

Pink Zone Luncheon honors researchers, clinicians, survivors

Author: Gene Stowe and Stephanie Healey

Mary Hesburgh Flaherty, a 1979 Notre Dame alumna and two-time breast cancer survivor, spoke about her experience with cancer at the third annual Pink Zone Luncheon on Feb. 2. Each year the luncheon is hosted by the College of Science and the Notre Dame women’s basketball team to honor breast cancer researchers, clinicians, and...

M. Sharon Stack accepts invitation to join editorial board of the journal Cancer Research

Author: Stephanie Healey

M. Sharon Stack, Ann F. Dunne and Elizabeth Riley Science Director of the Harper Cancer Research Institute and professor of chemistry and biochemistry, was recently named to the board of the journal Cancer Research. Her term will last from January 1, 2013 to December 21, 2015. Cancer Research is a bi- monthly journal that publishes...

Notre Dame research may have important implications for combating diabetes

Author: William G. Gilroy

Research by University of Notre Dame biochemist Anthony S. Serianni is providing new insights that could have important implications for understanding and treating diabetes. Serianni points out that biological compounds known as dicarbonyl sugars are produced inside the human body from the natural breakdown of the simple sugar glucose. The...

Researchers collaborate to seek FDA approval for drug treatment for rare disease

Author: Gene Stowe and Marissa Gebhard

University of Notre Dame alumnus Norbert Wiech founded Lysomics LLC to manage the clinical development needed to bring to market a promising new treatment for people with Niemann-Pick Type C (NPC) disease. FDA support is being sought for early clinical exploration of an approved drug to fight this rare disease...

Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment

Author: Arnie Phifer

Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow.   One of the difficulties doctors face in treating MM comes from the fact that cancer cells of this...

Notre Dame entomologists help discover new species of malaria-transmitting mosquito

Author: William G. Gilroy and Sarah Craig

Photo courtesy of Jenny Stevenson, LSHTM. University of Notre Dame entomologists are part of a team of researchers that recently discovered a potentially dangerous new malaria-transmitting mosquito. The as-yet-unnamed, and previously unreported, mosquito breeds in the western areas of Kenya and has an unknown DNA match to any of the...

New research could provide new insights into tuberculosis and other diseases

Author: William G. Gilroy

Researchers Patricia A. Champion and Matthew Champion from the University of Notre Dame’s Eck Institute for Global Health have developed a method to directly detect bacterial protein secretion, which could provide new insights into a variety of diseases including tuberculosis. The Champions demonstrated that their new method is applicable to...

Notre Dame researcher’s paper examines the biology and clinical application of tumor-derived microvesicles

Author: William G. Gilroy

A new paper by Crislyn D’Souza-Schorey, professor of biological sciences at the University of Notre Dame, discusses the biology of tumor-derived microvesicles and their clinical application as circulating biomarkers. Microvesicles are membrane-bound sacs released by tumor cells and can be detected in the body fluids of cancer patients.

Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment

Author: Arnie Phifer

Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow. One of the difficulties doctors face in treating MM comes from the fact that cancer cells of this type...

International researchers collaborate at Parseghian scientific conference

Author: Marissa Gebhard

Thirty researchers from universities and institutions around the world are presenting at the 2012 Michael, Marcia and Christa Parseghian Scientific Conference for Niemann-Pick Type C Research June 7 to 9 (Thursday to Saturday) in the Jordan Hall of Science at the University of Notre Dame. Niemann-Pick Type C (NPC) disease...