Special Seminar "Deciphering the Mechanism of Complex Biomolecular Interactions Using Advanced Computational Methods" Originally published at chemistry.nd.edu.

Dissertation title: "Understanding the Effects of the Inflammatory Response During Catheter-Associated Urinary Tract Infections: Roles of Fibrin(ogen) and Interleukin-6 in Promoting Infections and Targeted Anti-Inflammatory Therapeutics to Mitigate Infections" Advisor: Ana Flores-Mireles…

     CBBI "TBA"

     CBBI "TBA" Carlos Cal y Mayor Luna "TBA" Johann Roque

CBBI "Determination of the Antigenic Specificities of Alloreactive T Cells Driving Transplant Rejection" Chukwunalu Chukwuma.

 CBBI "Discovery of the Bacterial Topoisomerase Inhibitor OSUAB-0284, a Development Candidate for Drug-resistant Bacterial Infections"

     Biochemistry Seminar “Engineering Covalent Small Molecule-RNA Complexes in Living Cells”      Zoom Link: https://notredame.zoom.us/j/3785469853?pwd=TEZCckZpRGdqcitzVU9TTnZoeDFWZz09…

Dissertation title: "Innovative Approaches and Tool Development for Proteomics Data Analysis: Applications Across Diverse Biological Systems".  

Reilly Lecture I "Implantable Biochemical Sensors: A Shift from Reactive to Proactive Management of Disease and Health"

 CBBI "The Development and Evaluation of TRAP1 Selective Inhibitors" Andrew Gutierrez "Structural Insights and Immunogenic Enhancement of KRAS Neoantigen Recognition by TCRs in Cancer Immunotherapy" Bassant Eldaly  Originally published at chemistry.nd.edu.

 Reilly Lecture II "Electrochemical Biomolecular Sensing of Markers of Disease and Health" Originally published at chemistry.nd.edu.

The College of Science, Hesburgh Library, the Boler-Parseghian Center for Rare Diseases, and the Patient Advocacy Initiative at the University of Notre Dame are joining others around the world to show support for those affected by rare disease. Join us as we #LightUpForRare the Word of…

     Warren Center Lecture Like a Champion Series "Functionalized Membranes that Facilitate Protein Capture, Digestion and Analysis"   Merlin Bruening "Leveraging Molecular Genetics to Connect Protein Modification to Mycobacterial Pathogenesis"    Patricia Champion…

     CBBI "New Strategies for Anticancer and Antibacterial Drug Discovery"

     (Graduate Students Initiated) IMPACT Lecture Series "Rethinking the Cellular Stress Response" Abstract:   Cells across the tree of life respond to sudden unfavorable changes--stresses--in similar ways. Following a range of primordial stresses such as heat…

     Physical/Analytical Seminar "New Conjugated Materials for Biophysical, Quantum, and Electrochemical Applications" Abstract:  Conjugated oligoelectrolytes (COEs) and conjugated polyelectrolytes (CPEs) have emerged as leading materials in bioanalytical and electrochemical…

Dissertation title: "Avoidance of Intracellular Hsp90α Inhibition, Including Cell-Impermeable Extracellular Hsp90α (eHsp90α)-selective Inhibitors and Hsp90β-selective Inhibitors as Safer Alternatives" Advisor: Brian Blagg

Title: "Computational Elucidation of Enzyme Mechanisms: A Case Study on PmHMGR" Advisor: Olaf WiestCo-Advisor: Paul Helquist

Dissertation title: "Elucidating Ciliopathies: The Role of Empty Spiracles Homeobox 2 and Cannabinoid Signaling in Cilia Development Across Embryonic Tissues" Advisor: Rebecca Wingert

Dissertation title: "Further Characterization of a Novel Microtubule Binding Protein, ClipR-76, and Its Role in Cardiomyocyte Development"

     Jeremiah P. Freeman Organic Syntheses Lectureship "Rewriting Protein Modification" Abstract:  Nature regulates many biological processes through post-translational modifications that modify protein activity and relay signals through protein networks. Interpretation…

     Warren Center Lecture Like a Champion Series "Predicting Small Molecule Binding to Cryptic Protein Pockets Formed by Dynamic Loops"   Brittany Morgan "Our Journey from Antibiotic Resistance to Vaccine Development"   Michael McConnell Originally…

  CBBI "Next Generation Carbohydrate-based Vaccines Against Lethal Challenges of Staphylococcus Aureus”

Tentative Schedule: 8:30-9:00 am light refreshments = coffee and breakfast snacks 9:00-9:30 faculty talk 1 9:30-10:00 faculty talk 2 10:00-10:30 trainee talks 1-2 10:30-11:00 break 11:00-11:30 faculty talk 3 11:30-12:00 faculty talk 4 12:00-1:15 lunch 1:15-1:45 faculty talk 5 1:45-2:15 faculty talk…

     Biochemistry Seminar "Discovery and Engineering of the Antibody Response to a Prominent Skin Commensal"      Paper Link:   https://www.nature.com/articles/s41586-024-08489-4…

Dr. Celeste Karch, Professor of Psychiatry, Washington University School of Medicine in St. Louis “Defining molecular drivers of tauopathy using stem cell models” Originally published at biology.nd.edu.

"Targeting Protein Stability to Treat Misfolding Diseases” Originally published at chemistry.nd.edu.

Mario De Florio Brown University 154 Hurley Hall3:30 pm - 4:30 pm Scientific Machine Learning for Dynamical Systems Indentification The advancement of Physics-Informed Machine Learning (PIML) methods will empower scientists to swiftly and effectively address unresolved…

Dissertation title: "ClpX as a tool for assessing the impact of rate and direction of vectorial protein appearance on folding outcome" Advisor: Dr. Patricia Clark