Dissertation title: "Roles for Spatiotemporal Intracellular pH Dynamics in Single-Cell Phenotypes and Behaviors" Advisor: Katharine White

     Special Seminar "Antibody-carbohydrate Conjugates: Versatile Platforms for Ligand Discovery and Immunotherapy"

     CBBI "TBA"

     CBBI "TBA" Andrew Gutierrez "TBA" Avraz Anwar

     CBBI "TBA" Hannah Marietta "TBA" Tyelor Reynolds

     CBBI "TBA" Praise Chukwunalu Chukwuma "TBA" Amr El-Araby

Title: "Determining Why a Quorum Sensing Mutant Overproduces a Type IV Pili Dependent Phage inPseudomonas aeruginosa."

Title: "Exploring Covalent Chemistry in Ribonucleotides, Long Non-Coding RNA, and the Transcriptome"

Dissertation title: "Examining the Impact of E. Faecalis on P. Aeruginosa Metabolism and Behavior"  

Title: "Novel Strategy to Block Obesity Induced SREBP1 Activity Via HSP90β-Selective Inhibition for Ovarian Cancer"

Title: "Avoidance of Intracellular Hsp90α Inhibition, Including Cell-Impermeable Extracellular Hsp90α (eHsp90α)-selective Inhibitors and Hsp90β-selective Inhibitors as Safer Alternatives"

     Biochemistry Seminar "Single Cell RNA Sequencing in Kidneys Reveals SGLT2 Inhibitor Impact in Youth-onset Type 2 Diabetes"

"Monitoring the Movement of Molecules in the Body via Real-time Aptamer-based Sensors" Abstract:   Electrochemical, aptamer-based sensors (E-ABs) enable specific, continuous, and real-time molecular measurements in vivo. Their selectivity and modularity stem from the use of nucleic acid aptamers—single-stranded DNA oligos selected in vitro for their ability to bind specific molecular targets. To create E-ABs, redox-reporter-modified aptamers are attached to gold electrodes via thiol-based self-assembly. These modified aptamers are engineered to exhibit two thermodynamic states: an unbound, slow electron-transferring state in the absence of the target, and a bound, fast electron-transferring state in the presence of the target. The two...

Justin Webster University of Maryland, Baltimore County 154 Hurley Hall3:30 pm - 4:30 pm Stability and Periodicity in PDE Systems Time-periodic behavior can arise in multi-physics systems as (i) a response to periodic forcing (blood flow in human tissues) or (ii)…

Hui Zhang Northwestern Medicine, Feinberg School of Medicine 3:45 PM127 Hayes-Healy CenterA tea will precede the event at 3:15 pm…

     CBBI "Targeting Histone Deacetylases for Cancer Therapy and Beyond"

     Warren Center Lecure Like a Champion Series "Elucidating Small Molecule-DNA Binding Mechanisms with Molecular Dynamics Simulations" Steven Corcelli "Computational Studies of Ebola VP40, the Swiss Army Knife of Proteins" Olaf Wiest

Former William K. Warren Foundation Dean of the Notre Dame College of Science, Gregory P. Crawford, who is now the 22nd president of Miami University; Sean Kassen, director of the Ara Parseghian Medical Research Fund; Barbara Calhoun, assistant professor of the practice and the Reisenauer Family Director…

Bayesian Weighted Learning in Dynamic Treatment Regime

Please join the Department of Biological Sciences for a seminar featuring Dr. Christopher Patzke, John M. and Mary Jo Boler Assistant Professor. Originally published at biology.nd.edu.

Dissertation title: "Elucidating the Genetic Determinants of Drug Response in Plasmodium falciparum" Advisor: Michael Ferdig Contact Cheryl Schairer for Zoom link, cschaire@nd.edu

     CBBI "Exploring Peptidoglycan Glycosidases as Targets for Developing Novel Antimicrobial Therapeutic Strategies"

Title: "Defining the fungal-host interactions between the pathogenic yeast Cryptococcus neoformans and human microglia"

Notre Dame Research invites you to participate in the 2024 Core Facility Fair.…

Register here …

Please join the Department of BIological Sciences for a seminar featuring Dr. Fernanda Novais, Assistant Professor in the Department of Microbial Infection and Immunity at The Ohio State University. Originally published at biology.nd.edu.

Title:"Structural Insights and Immunogenic Enhancement of KRAS Neoantigen Recognition by TCRs in Cancer Immunotherapy"

Title: "Systematic Discovery of Molecular Glues"

(Graduate Students Initiated)      IMPACT Lecture Series "Synthetic Studies and Applications of Complex Natural Products"