Neoantigens, which are molecules found on tumor cells that incorporate mutations, help our immune system fight cancers and could be the most promising components of future cancer vaccines—if only scientists knew with a high degree of certainty which neoantigens work. A collaboration of scientists…

In a new study in NPJ Genomic Medicine, researchers at the University of Notre Dame have found that a largely understudied cell could offer new insight into how the aggressive, primary brain cancer is able to resist immunotherapy.

Four PhD students at the University of Notre Dame have joined the Eck Institute for Global Health as graduate research fellows. The Institute will support the students as they pursue topics…

Although it’s well-known that fragile X is caused by the FMR1 gene, it’s less understood how the disorder physically affects brain development and function. Christopher Patzke at the University of Notre Dame is collaborating with fragile X patients and families to study the disorder.

Researchers have developed a new, lightning-fast method to detect “extracellular RNA,” or exRNA, which will aid in early detection of diseases including cancer, heart disease, HIV and other life-threatening conditions.

What happens when previously treatable cancers become drug-resistant? Jianneng Li, Archibald Assistant Professor in the Department of Biological Sciences, is trying to answer that question by conducting critical research on prostate cancer.

Researchers at the University of Notre Dame have conducted an analysis of the World Mosquito Program’s randomized control trial of Wolbachia-infected mosquitoes in Indonesia, looking at how excluding transmission dynamics impacted the original interpretation of the trial’s results.

Saurja DasGupta, assistant professor in the Department of Chemistry and Biochemistry, attempts to pull back the curtain on four-plus billion years of history to investigate the origins of life itself. “My lab is interested in studying…

In the fight against metastatic cancer, harnessing a patient’s own immune system to target cancer cells has been a promising strategy. In a recent article published in Cell Metabolism, Xin…

Santiago Schnell, the William K. Warren Foundation Dean of the College of Science, will receive the Distinguished Scientist…

Santiago Schnell, William K. Warren Foundation Dean of the College of Science at the University of Notre Dame, has been appointed to a new statewide advisory council to explore new directions for assisting patients with…

Postdoctoral researcher Tolulope “Kay” Kayode won the top prize in the second annual Postdoc Lightning Talk Competition on Thursday, September 21, during Postdoc Appreciation Week.  …

During fiscal year 2023, the University of Notre Dame received nearly $216 million in new research award funding, topping $200 million for the third year in a row. This total includes 824 separate awards, the largest number the University has ever received.

Cancer researchers at the University of Galway and Notre Dame’s Harper Cancer Research Institute have come together to establish the Biseach Initiative, a strategic cancer research collaboration, which aims…

Holly Goodson, Professor of Chemistry & Biochemistry, has been selected as a Fellow of The American Society for Cell Biology (ASCB). She joins 18 other distinguished scientists from across the globe in the 2023 cohort of fellows. Her formal recognition will take place in Boston later this year at Cell...

A new study links a high body mass index (BMI) to alterations in the structure and environment of cancerous tumors. Most women with ovarian cancer are diagnosed with the most advanced form of the disease. Less than a third of those diagnosed with the disease survive five years later.…

Tom Nee speaking with students before demonstrating how to shear a sheep. The University…

A decade ago, Shrout began collaborating with Paul Bohn, the Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering and director of Notre Dame’s Berthiaume Institute for Precision Health. Bohn’s lab specializes in creating new technologies for more precise analysis of cells and molecules. Together, Bohn and Shrout began searching...

The Early Career Development (CAREER) awards provide support to early career faculty members who exhibit the potential to “serve as academic role models” and “lead advances in the mission of their department or organization.” Since 2014, Notre Dame faculty have earned 68 of these nationally competitive awards.

Patricia A. Champion, Ph.D., has been appointed the next Associate Dean for Research, Graduate and Postdoctoral Studies effective July 1, 2023. She replaces Michael Hildreth, who transitions to his…

The first Seed Transformative Interdisciplinary Research (STIR) grants, announced in early 2023 by the Notre Dame College of Science and College of Engineering, have been awarded to four new research projects led by multidisciplinary teams of scientists and engineers. The one-year seed grants…

Groundbreaking science can happen where disciplines intersect, and scientists team up.

A new study in the Journal of Cell Science by University of Notre Dame researchers could eventually lead to therapies that will limit cancer cells’ ability to grow and divide.

The University of Notre Dame has been selected for inclusion in the Association of American Universities (AAU), a consortium of the nation’s leading public and private research universities, Notre Dame’s president, Rev. John I. Jenkins, C.S.C., announced today.

Dr. Fu reviewed his research with aptamer-based electrochemical biosensors, which allow for operation in complex samples, like living organisms.

On Tuesday (May 23), John T. McGreevy, the Charles and Jill Fischer Provost at the University…

New study reveals increased complexity of drug resistance …

University of Notre Dame researchers discovered that an oxadiazole antibiotic—a compound of a previously discovered class that treats MRSA—kills C. diff. and prevents the germination of its spores.

Sheri Sanders considered becoming a veterinarian, but after one semester of coursework she realized she preferred working in a laboratory and tinkering with programming.  

Assistant Professor Giuseppe Vinci in the Department of Applied and Computational Mathematics and Statistics likes to make sure students take interdisciplinary approaches with their research. Students Matthew Baumstark and Lauren Beede are working on  research projects that combine their different interests.