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News » Archives » May 2014

New paper provides important insights into how carcinoma-associated fibroblasts function in breast cancers

Author: William G. Gilroy

Carcinoma-associated fibroblasts (CAFs)

A new paper by a team of researchers led by Zachary T. Schafer, Coleman Assistant Professor of Cancer Biology in the Department of Biological Sciences at the University of Notre Dame, offers important new insights into the role carcinoma-associated fibroblasts (CAFs) play in tumor biology.

A number of recent studies have revealed CAFs to be a major contributor to tumor progression through a variety of mechanisms. Despite this information, the precise role CAFs play in augmenting the growth of tumors is still poorly understood. Read More

Targeting Cancer

Author: Angela Cavalieri

At the Harper Cancer Research Institute, Notre Dame professor Z. Basar Bilgicer has found a way to focus chemotherapy on cancer cells while leaving healthy cells untouched.

By Michael Rodio ’12 | Apr. 23, 2014


In the fight against cancer, chemotherapy is a race against time. While chemotherapy kills the tumor, it also kills healthy tissue. So chemotherapy must do its job—eliminate cancerous growth Read More

Researchers in the Wingert lab identify new genetic components involved in kidney development

Author: Rebecca Wingert

Christina Cheng, Zoe Li, Valerie Verdun, and Rebecca Wingert
Christina Cheng, Zoe Li, Valerie Verdun, and Rebecca Wingert

A study conducted by a team of scientists in the laboratory of Rebecca Wingert, Assistant Professor, Elizabeth and Michael Gallagher Family Professorship in Adult Stem Cell Research in the Department of Biological Sciences, has provided novel insights into the genetic program of kidney cell development. Read More