A team of University of Notre Dame scientists, in collaboration with researchers at the University of Connecticut, have announced the results of a new study on identifying potential targets for personalized cancer vaccines. The paper, “Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity,” was...

The University of Notre Dame and Feinstein Institute for Medical Research have announced a plan to collaborate on biomedical research projects, student training, joint conferences and other forms of academic exchange. The Feinstein Institute was founded in 1999 to host the research operations for the North Shore-LIJ Health System. As...

Zachary T. Schafer, Coleman Assistant Professor of Cancer Biology at the University of Notre Dame, has been awarded a Research Scholar Grant from the American Cancer Society (ACS).

The largest outbreak of the Ebola virus in history currently occurring in West Africa has raised fears that the disease may soon spread to the United States. However, a University of Notre Dame researcher who studies the virus believes that, while there are grounds for concern, there is no need...

When it comes to a cancer diagnosis, timing can be everything. An early diagnosis can make a big difference when it comes to treatment possibilities. Pancreatic Ductile Adenocarcinoma (PDAC) has a 5 year survival rate of 6% according to Dr. Reginald Hill, Archibald Assistant Professor of Cancer Biology at the...

Nearly 50 scientists gathered at the University of Notre Dame on Sunday and Monday for the Indiana-Illinois End Epithelial Ovarian Cancer Coalition (IIEEOCC) workshop, an effort to advance collaboration and research on a deadly form of cancer that affects over 20,000 women a year.   Read more....

A new paper by a team of researchers led by Zachary T. Schafer, Coleman Assistant Professor of Cancer Biology in the Department of Biological Sciences at the University of Notre Dame, offers important new insights into the role carcinoma-associated fibroblasts (CAFs) play in tumor biology. A number of recent studies...

The Research Like a Champion competition winners were recently announced at the Harper Cancer Research Institute’s third annual research day. The donor who sponsored the competition was so impressed by the pool of research projects that he generously decided to provide funding for three projects.

At the Harper Cancer Research Institute, Notre Dame professor Z. Basar Bilgicer has found a way to focus chemotherapy on cancer cells while leaving healthy cells untouched. By Michael Rodio ’12 | Apr. 23, 2014   In the fight against cancer, chemotherapy is…

Christina Cheng, Zoe Li, Valerie Verdun, and Rebecca Wingert…

Now that the human genome is sequenced, University of Notre Dame researchers are focusing on the study of the proteome, which is the protein content of an organism, tissue or cell. Bioanalytical chemist Norman Dovichi and molecular biologist Paul Huber have successfully tracked the changing patterns of protein expression during...

Notre Dame physicists investigate plasma tool for destroying cancer cells Notre Dame researchers led by Sylwia…

University of Notre Dame biologists Nicole Achee and Neil Lobo are leaders of an international $23 million research grant from the Bill & Melinda Gates Foundation. Their five-year project will generate the data required to show the effectiveness of a new paradigm in mosquito control — spatial repellency — for...

The William K. Warren Foundation of Tulsa, Okla., has made a $3.5 million gift to the University of Notre Dame that, combined with a previous gift valued at $6.5 million, will endow the creation of The Warren Family Research Center for Drug Discovery and Development in the College of Science....

A new research paper from the labs of University of Notre Dame researchers Holly Goodson and Mark Alber helps resolve an ongoing debate about the assembly of a subcellular network that plays a critical role in cell function and disease.

Standing at a microscope in her Harper Hall laboratory, Karen Cowden Dahl, adjunct assistant professor of chemistry and biochemistry at the University of Notre Dame and assistant professor of biochemistry and molecular biology at the Indiana University School of Medicine-South Bend, is scanning through a petri dish filled with cancer...

The University of Notre Dame and Loyola University Chicago are joining forces in a multidisciplinary cancer research collaboration. The goal of the alliance is to provide direct support for revolutionary new cancer research, with the ultimate objective of making cancer a more manageable, and potentially curable, disease.

Irregular expressions of a panel of regulatory microRNAs (miRNA) in blood and other physiological fluids may allow early screening of many kinds of cancer. However,  the current technologies for identifying and quantifying small numbers of these short (22 bases) molecules in physiological samples require expensive instrumentation and extensive personnel. These...

Cancer’s origin point—a human gene gone haywire—is, in many cases, also its weak spot. If you could block the abnormal function of a gene that is important for metastasis, the theory goes, then maybe you can stop cancer from spreading. But there’s a catch—hit the weak spot with too much...

University of Notre Dame researchers have, for the first time, identified the enzymes that are detrimental to diabetic wound healing and those that are beneficial to repair the wound. There are currently no therapeutics for diabetic wound healing. The current standard of care is palliative to keep the wound clean...