Apply Now

News » Archives » February 2011

Notre Dame researchers discover dual-action compound for potential treatment of tuberculosis and malaria

Author: Julie Hail Flory

Plasmodium falciparum

Marvin Miller, the George and Winifred Clark Chair in Chemistry, and Michael Ferdig, associate professor of biological sciences at the University of Notre Dame, are co-authors of a study recently published in the Journal of the American Chemical Society on a potential breakthrough in the fight against tuberculosis and malaria—global diseases that each kill some 2 million people a year.

In an interdisciplinary project, the researchers synthesized an iron transport molecule attached to an antibiotic that the tuberculosis bacterium would gladly ingest as a “Trojan horse,” a method that has proven to be successful for the Miller lab in other studies. Read More