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Blue-sky biomedical projects launched by new funding

Author: Arnie Phifer

Innovative research includes efforts to treat Parkinson’s disease, understand heart disease and strokes, tackle bacterial drug resistance     Advanced Diagnostics & Therapeutics (AD&T), a strategic research initiative at the University of Notre Dame, has announced the recipients of its Discovery Fund awards for 2016. Each year, these awards are...

Notre Dame students on the front lines of medical research

Author: Arnie Phifer

New fellowships enable summer research at New York’s largest health system   Two Notre Dame undergraduate students—Anne Grisoli and Richard Felli—and two graduate students—Katelyn Ludwig and Steve Marczak—spent the summer of 2016 conducting laboratory and clinical research at the Feinstein Institute for Medical Research in New York. All four are...

Uncovering a new pathway to halting metastasis

Author: William G. Gilroy

Metastasis, the process by which cancer cells leave the primary tumor and spread to other sites in the body, is responsible for more than 90 percent of cancer deaths. Thus, there is a significant need to improve the therapeutic options for patients who suffer from metastatic disease. New research from...

Katherine Ward finds niche in the convergence of science and business

Author: Brian Wallheimer

Katherine Ward enrolled as a graduate student at Notre Dame with her sights set on academia and work that would help people like her father, who had long suffered from serious back pain. She had watched for many years as his diagnosis would change, but the pain wouldn’t go away....

Identifying Effective Treatments for Colon Cancer

Author: Brandi Klingerman

Notre Dame researcher uses tumor cells to evaluate the effectiveness of current medications Amanda Hummon, Huisking Foundation, Inc. Associate Professor of Chemistry and Biochemistry In recent years researchers have begun to understand that the development of colon cancer, which is the second most common cancer in the United States, can...

Preventing Infections in Prosthetic Hip Joint Replacements

Author: Brandi Klingerman

Notre Dame researcher explores bacteria beyond the ability of typical hospital setting  Gail Weaver, post-doctoral research associate Each year 332,000 total hip replacements are performed in the United States, according to the Centers for Disease Control and Prevention. Out of those, nearly one percent of patients will get an infection...

A Personal Vendetta against Cancer

Author: Brendan O'Shaughnessy

Cancer survivor builds tissue bank for Harper Cancer Research Institute Toni Page-Mayberry, tissue bank consent coordinator at the Harper Cancer Research Institute These days, Page-Mayberry funnels that passion into her job as the tissue bank consent coordinator for the Mike and Josie Harper Cancer Research Institute at Notre Dame. Her...

Holding the Key to Affordable Biotherapeutics

Author: Brandi Klingerman

Notre Dame researcher explores the potential of producing mammalian-like proteins with silkworm moths Professor Malcolm Fraser Jr. The availability of medicines in many low- and middle-income countries is undermined by poor medicine supply, insufficient health facilities, and the high cost of medicine, according to the World Health Organization. This includes...

Network physicist sheds light on Alzheimer’s, schizophrenia

Author: Gene Stowe

Researchers comparing mouse and macaque brains have found evidence of an evolutionary universal brain structure in mammals that enables comparisons of cortical networks between species. A new study from a researcher at the University of Notre Dame could provide insights into brain disorders such as Alzheimer’s and schizophrenia.

How Being Sick impacts a Person’s Behavior

Author: Sarah Craig

Alex Perkins, Ph.D., Eck Family Assistant Professor in the Departments of Biological Sciences and Applied and Computational Mathematics and Statistics, and a member of the Eck Institute for Global Health, recently published a study looking at behavior of patients with one of the most common symptoms of disease: fever.  Surprisingly,...

Women in Science Regional Conference to be held at Notre Dame

Author: Tiffanie Sammons

Women in Science Regional Conference Sept. 30 – Oct. 1, 2016 The Association for Women in Science (AWIS) at Notre Dame is hosting the first ever Women in Science Regional Conference on Sep. 30th – Oct 1st. Graduate students will have the opportunity to network with high profile professionals from across the US, attend career development workshops and participate...

Taking Multiple Myeloma Down for the Count

Author: Nina Welding

When battling cancer, everything is on the table. Radiation therapy. Surgery. Chemo. Advances in nanotechnology have enabled researchers, like Associate Professor Z. Basar Bilgicer, Research Assistant Professor Tanyel Kiziltepe, and their team in the Department of Chemical and Biomolecular Engineering at the University of Notre Dame, to encapsulate cancer-fighting/cancer-killing drugs...

Sharon Stack and Matt Ravosa, an academic couple: Researching cancer biology and evolution

Author: Carol Bradley

Sharon Stack and Matt Ravosa joined the University of Notre Dame in 2011, coming from positions at the University of Missouri School of Medicine in Columbia, Missouri. Stack is the Ann F. Dunne and Elizabeth Riley Director of the Harper Cancer Research Institute (HCRI) and the Kleiderer-Pezold Professor of Chemistry...

Experimental in Nature

Author: Jason Kelly '95

Notre Dame’s Harper Cancer Research Institute is trying a different strategy in the fight against the disease: bringing scientists from diverse fields onto a single team. Introducing herself around campus in 2011, biochemist Sharon Stack sought faculty far outside her academic background. She wanted to get a feel for the...

Collecting Compounds for the Treatment of Rare Genetic Disorders

Author: Brandi Klingerman

As Richard Taylor completes a three-year term as associate vice president for research in June of this year, he will continue his research on drug discovery for rare genetic diseases, like NGLY1 deficiency, when he and other members of the Warren Family Research Center for Drug Discovery and Development move into the...

Michael Hildreth is the Next Associate Dean for Research and Graduate Studies

Author: Tammi Freehling

Michael Hildreth is appointed the next Associate Dean for Research and Graduate Studies effective July 1, 2016. He replaces Brian Baker, who steps down as associate dean after three years of leadership. Says Hildreth of his new role, “I’m excited and humbled by this opportunity to increase the breadth and...

VWR supports Notre Dame Research to detect Low-Quality Medicines in Kenya

Author: Joya Helmuth

In partnership with the Notre Dame Initiative for Global Development (NDIGD), Professor of Chemistry Marya Lieberman and her research team have received support from VWR , a leading global independent provider of product and service solutions to laboratory and production customers.

Understanding the Molecular Structure of Compounds in order to Advance Discovery of New Medicines and More

Author: Brandi Klingerman

At the University of Notre Dame, the Molecular Structure Facility (MSF) analyzes organic or inorganic substances at an atomic level, which allows researchers to learn about the three-dimensional structure and connectivity of the compound they have created. Knowing the molecular make-up of substances oftentimes provides faculty, postdoctoral fellows, and graduate...

Harper Cancer Research Institute open house scheduled for June 28

Author: William G. Gilroy

The University of Notre Dame’s Harper Cancer Research Institute will hold an open house from 4 to 6:30 p.m. June 28 (Tuesday) in Harper Hall. The event is free and open to the public, and refreshments will be provided.

Engineering the immune system to kill cancer cells

Author: Tammi Freehling

In late 2015, former President Jimmy Carter announced that he was free of the metastatic melanoma that had spread to his liver and brain. In addition to surgery and radiation, Carter was treated with an immunotherapy drug, a new approach in cancer treatment that has a promising outlook.

Entomologist Nicole L. Achee helps write gene drives report

Author: William G. Gilroy

University of Notre Dame medical entomologist Nicole L. Achee is a member of a committee convened to summarize the scientific discoveries related to gene drives and considerations for their responsible use. The National Institutes of Health (NIH) and the Foundation for the National Institutes of Health asked the National Academies...

DoD grant funds pursuit of novel insecticides to fight Zika, other diseases

Author: Gene Stowe

A collaboration among faculty in the Eck Institute for Global Health and the Warren Family Research Center for Drug Discovery and Development is investigating new ways to kill the mosquitoes that carry the Zika virus, dengue fever, and other dangerous diseases.

Notre Dame Research to showcase Commercialization Opportunities at BIO 2016

Author: Brandi Klingerman

The University of Notre Dame will attend the 2016 BIO International Convention, which is hosted by the Biotechnology Innovation Organization (BIO) from June 6 - 9, 2016 in San Francisco. Represented Notre Dame Research groups at the event include the Harper Cancer Research Institute (HCRI), the Center for Nano Science and Technology...

Study reveals insights into protein linked to cancer and Alzheimer’s disease

Author: William G. Gilroy

Drugs to treat cancer and Alzheimer’s disease usually target the active sites of specific protein molecules sustaining the disease. Traditional drug design views proteins as rigid 3-D objects with active sites consisting of surface-accessible “pockets” with a specific, well-defined structure. Traditional drug design involves finding small molecules with shapes that...