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News » Archives » November 2013

Researchers gain new insights into brain neuronal networks

Author: Gene Stowe and Marissa Gebhard

A bow-tie representation of the network of connections between cortical areas in the brain

A paper published in a special edition of the journal Science proposes a novel understanding of brain architecture using a network representation of connections within the primate cortex. Zoltán Toroczkai, professor of physics at the University of Notre Dame and co-director of the Interdisciplinary Center for Network Science and Applications, is a co-author of the paper “Cortical High-Density Counterstream Architectures.” Read More

Notre Dame research finding may help accelerate diabetic wound healing

Author: William G. Gilroy

Mobashery Lab

University of Notre Dame researchers have, for the first time, identified the enzymes that are detrimental to diabetic wound healing and those that are beneficial to repair the wound.

There are currently no therapeutics for diabetic wound healing. The current standard of care is palliative to keep the wound clean and free of infection. In the United States, 66,000 diabetic individuals each year undergo lower-limb amputations due to wounds that failed to heal. Read More

The Silent Gene

Author: Angela Cavalieri

 

Dr. Jenifer Prosperi, a researcher at the Harper Cancer Research Institute, is studying how to treat breast cancers that evolve when a crucial tumor suppressor gene goes silent.



Over the past 15 years, the scientific community has come to understand that breast cancer is a monster with many faces.



Some cancers have one of three special indicator molecules (HER2, estrogen receptors and progesterone receptors) that can guide targeted anti-cancer treatments. But another set of breast cancers, the “triple-negative” types, lack those three indicator molecules that can guide treatment. And even now, the question remains: How can doctors better target and treat triple-negative cancers? And how can they keep up the treatment when breast cancers fight back? Read More