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News » Archives » June 2012

Notre Dame researcher’s paper examines the biology and clinical application of tumor-derived microvesicles

Author: William G. Gilroy

"Genes and Development," June 15, 2012

A new paper by Crislyn D’Souza-Schorey, professor of biological sciences at the University of Notre Dame, discusses the biology of tumor-derived microvesicles and their clinical application as circulating biomarkers. Microvesicles are membrane-bound sacs released by tumor cells and can be detected in the body fluids of cancer patients. Read More

Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment

Author: Arnie Phifer

A time-lapse image showing multiple myeloma cells internalizing the engineered nanoparticles

Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow.

One of the difficulties doctors face in treating MM comes from the fact that cancer cells of this type start to develop resistance to the leading chemotherapeutic treatment, doxorubicin, when they adhere to tissue in bone marrow.

“The nanoparticles we have designed accomplish many things at once,” says Başar Bilgiçer, assistant professor of chemical and biomolecular engineering and chemistry and biochemistry, and an investigator in Notre Dame’s Advanced Diagnostics and Therapeutics (AD&T) initiative. Read More

International researchers collaborate at Parseghian scientific conference

Author: Marissa Gebhard

Undergraduate Sue Yi at work on NPC in a laboratory

Thirty researchers from universities and institutions around the world are presenting at the 2012 Michael, Marcia and Christa Parseghian Scientific Conference for Niemann-Pick Type C Research June 7 to 9 (Thursday to Saturday) in the Jordan Hall of Science at the University of Notre Dame.

Niemann-Pick Type C (NPC) disease is a rare, fatal neurodegenerative disease for which there is no cure. The disease is an inherited cholesterol metabolism disorder that strikes primarily children before or during adolescence. One in every 150,000 children is affected by the disease with symptoms that include deterioration of memory and balance, lung and liver failure, delayed motor development and seizures. Through research collaboration, progress is being made on treatments for the disease. Read More

Dovichi receives Royal Society of Chemistry Prize for Analytical Science

Author: Rachel Fellman and Marissa Gebhard

Norman Dovichi

The Royal Society of Chemistry has announced that Norman Dovichi, the Grace-Rupley Professor of Chemistry at the University of Notre Dame, will be awarded the 2012 Robert Boyle Prize for Analytical Science.

The biennial prize is given to the candidate whose work is of the broadest relevance to the chemical science community as a whole and whose career is defined by exceptional work, excellence and dedication. It includes a £5,000 cash award, a medal and a lecture tour of the U.K. The prize will be formally presented Nov. 9 in Birmingham, England. Read More