Research by University of Notre Dame biochemist Anthony S. Serianni is providing new insights that could have important implications for understanding and treating diabetes. Serianni points out that biological compounds known as dicarbonyl sugars are produced inside the human body from the natural breakdown of the simple sugar glucose. The...

University of Notre Dame alumnus Norbert Wiech founded Lysomics LLC to manage the clinical development needed to bring to market a promising new treatment for people with Niemann-Pick Type C (NPC) disease. FDA support is being sought for early clinical exploration of an approved drug to fight this rare disease...

Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow.   One of the difficulties doctors face in treating MM comes from the fact that cancer cells of this...

Photo courtesy of Jenny Stevenson, LSHTM. University of Notre Dame entomologists are part of a team of researchers that recently discovered a potentially dangerous new malaria-transmitting mosquito. The as-yet-unnamed, and previously unreported, mosquito breeds in the western areas of Kenya and has an unknown DNA match to any of the...

Researchers Patricia A. Champion and Matthew Champion from the University of Notre Dame’s Eck Institute for Global Health have developed a method to directly detect bacterial protein secretion, which could provide new insights into a variety of diseases including tuberculosis. The Champions demonstrated that their new method is applicable to...

A new paper by Crislyn D’Souza-Schorey, professor of biological sciences at the University of Notre Dame, discusses the biology of tumor-derived microvesicles and their clinical application as circulating biomarkers. Microvesicles are membrane-bound sacs released by tumor cells and can be detected in the body fluids of cancer patients.

Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow. One of the difficulties doctors face in treating MM comes from the fact that cancer cells of this type...

Thirty researchers from universities and institutions around the world are presenting at the 2012 Michael, Marcia and Christa Parseghian Scientific Conference for Niemann-Pick Type C Research June 7 to 9 (Thursday to Saturday) in the Jordan Hall of Science at the University of Notre Dame. Niemann-Pick Type C (NPC) disease...

The Royal Society of Chemistry has announced that Norman Dovichi, the Grace-Rupley Professor of Chemistry at the University of Notre Dame, will be awarded the 2012 Robert Boyle Prize for Analytical Science. The biennial prize is given to the candidate whose work is of the broadest relevance to the chemical...

Greg Crawford, dean of the College of Science at the University of Notre Dame, will be cycling 3,250 miles from Boston to Pebble Beach, Calif., to raise awareness and funds for research to find a cure for Niemann-Pick Type C (NPC) disease. His third cross-country ride will start May 21...

Harper Cancer Research Institute (HCRI) Research Day on April 23 (Monday) will gather cancer researchers from the University of Notre Dame and Indiana University School of Medicine-South Bend (IUSM-SB) in an afternoon of exchange and discussion. A keynote address by Beatrice Knudsen, M.D., Ph.D., will discuss “Tissue Banking for Genomic...

Researchers from the University of Notre Dame’s Eck Institute for Global Health have developed a “gene chip” to contribute to the identification of malaria drug resistance, an effort that will allow for real-time response in modified treatment strategies for this devastating disease. The discovery is described in a paper appearing...

University of Notre Dame Professor Jeff Schorey, associate director of the Eck Institute for Global Health and a member of the Center for Rare and Neglected Diseases, is part of a team of researchers who received one of 10 new Grand Challenges in Global Health (GCGH) Grants from the Bill...

A multi-university research group which includes several University of Notre Dame faculty and graduate students, has recently published a paper detailing new work on the analysis and dating of human bruises. The research, which is funded by the Gerber Foundation, will have particular application to pediatric medicine, as bruise age...

A team of researchers led by Kasturi Haldar and Souvik Bhattacharjee of the University of Notre Dame’s Center for Rare and Neglected Diseases has made a fundamental discovery in understanding how malaria parasites cause deadly disease. The researchers show how parasites target proteins to the surface of the red blood...