Apply Now

News » Archives » April 2011

Notre Dame chemist sheds new light on antibiotics and the survival of bacteria

Author: Julie Hail Flory

Shahriar Mobashery

Research in the laboratory of Shahriar Mobashery in the University of Notre Dame’s Department of Chemistry and Biochemistry has led to further understanding of how a bacterial cell wall cross-links, an event that penicillin and other antibiotics disrupt, a step in the maturation of a cell wall that is critical for the survival of bacteria.

Mobashery is the Navari Family Chair in Life Sciences at Notre Dame. His group published the findings recently in the Journal of the American Chemical Society in an article titled, “A Computational Evaluation of the Mechanism of Penicillin-Binding Protein-Catalyzed Cross-Linking of the Bacterial Cell Wall.” Read More