Cellular & Molecular Biology
Researchers in the IBMS Cellular & Molecular Biology cluster use multifaceted experimental approaches to understand the molecular mechanisms of biological processes and their contribution to the function of cells, tissues, and organisms. Ongoing research ranges from investigations of fundamental molecular processes - such as regulation of gene expression, intracellular trafficking, cellular homeostasis, and cell division - to studies of cellular differentiation and the development of complex, multicellular biological structures. Students in the cluster will gain an appreciation of the molecular and cellular underpinnings of biological form and function.
Image: Deconvolution microscopy of mitotic cells showing the spindle assembly checkpoint. Image courtesy of the laboratory of Kevin Vaughan.
Contact
Xin Lu (website>)
Department of Biological Sciences
Contact by email
(574) 631-6592
Participating Faculty
Alvaro Acosta SerranoBiological Sciences |
We study the biology of kinetoplastid parasites and their insect vectors using biochemical, molecular and cellular approaches and develop new tools to prevent transmission of vector-borne pathogens
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Katrina AdamsBiological Sciences |
We ask how different populations of neural stem and glial progenitor cells within the mammalian brain respond to injury and disease including in individuals with Multiple Sclerosis |
Francis CastellinoChemistry and Biochemistry |
In vitro and in vivo relationships between hemostasis and inflammation |
Patricia A. ChampionBiological Sciences |
Molecular genetics of mycobacterial protein secretion and pathogenesis |
Patricia L. ClarkChemistry and Biochemistry |
Protein biophysics in living cells |
Saurja DasGuptaChemistry and Biochemistry |
RNA structure, function, and evolution, RNA Biology, Origins of life |
Crislyn D'Souza-SchoreyBiological Sciences |
Signal integration and cancer progression |
Ana Lidia Flores-MirelesBiological Sciences |
Molecular, Cellular, and Immunological Analysis of the Pathogenesis of Catheter-associated Infections |
Kelsey GasiorApplied & Computational Mathematics & Statistics |
Using an interdisciplinary approach to understand the multiscale dynamics controlling spatio-temporal patterns necessary for cellular function |
Holly GoodsonChemistry and Biochemistry; Biological Sciences |
Molecular and cell biology and biophysics |
Kasturi HaldarBiological Sciences |
Understanding disease pathology and developing treatments in rare and neglected diseases |
David R. HydeBiological Sciences |
Visual System Development and Dysfunction |
Shaun LeeBiological Sciences |
Molecular microbiology and biosynthesis of peptide antibiotics |
Jianneng LiBiological Sciences |
My laboratory focuses on the functions of steroid hormones including their precursors and receptors in prostate cancer as well as related diseases |
Laurie LittlepageChemistry and Biochemistry |
Modeling cancer progression in vivo to develop biomarkers and therapies; contributions of the microenvironment to breast and prostate cancers
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Xin LuBiological Sciences |
Molecular Understanding and Immunotherapy of Metastatic Cancer; Novel Animal Models for Rare Cancers |
Mary Ann McDowellBiological Sciences |
Immunoparasitology |
Joseph O'TousaBiological Sciences |
Photoreceptor function and processes of retinal degeneration |
Christopher PatzkeBiological Sciences |
Human Neurons and Synapses: Development, Function and Disease |
Jenifer ProsperiBiochemistry and Molecular Biology (IUSM-SB) and Biological Sciences (ND) |
Breast cancer biology and chemotherapeutic resistance |
Felipe H Santiago-TiradoBiological Sciences |
Cryptococcal cell biology and host interactions important for disease
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Zachary SchaferBiological Sciences |
Cancer cell biology and metabolism |
Molly Duman ScheelMedical and Molecular Genetics (IUSM-SB) and Biological Sciences (ND) |
Genetic and comparative analysis of invasive cellular growth; vector mosquito developmental genetics |
Jeff SchoreyBiological Sciences |
Immunology and Cell Biology of Mycobacterium - Host Cell Interactions |
Margaret SchwarzPediatrics (IUSM-SB) and Chemistry and Biochemistry (ND) |
Anti-angiogenic factors in lung and tumor development |
Joshua ShroutCivil & Environmental Engineering & Earth Sciences; Biological Sciences |
Bacterial biofilms, cell-cell signaling, and surface motility |
Cody J. SmithBiological Sciences |
Development and Regeneration of the Nervous System |
Sharon StackChemistry and Biochemistry |
Proteolysis and adhesion in cancer metastasis |
Richard TaylorChemistry and Biochemistry |
Synthetic organic chemistry; polyketide natural products as chemotherapeutic agents |
Kevin VaughanBiological Sciences |
Molecular basis of organelle transport |
Katharine WhiteChemistry and Biochemistry |
Cellular pH dynamics; pH-sensitive mechanisms regulating proteins, pathways, and cancer cell behaviors |
Rebecca WingertBiological Sciences |
Developmental biology and regeneration |
Jeremiah ZartmanBiological Sciences |
systems biology of organ growth and regeneration; reverse-engineering signaling networks and biophysical mechanisms that regulate cell decisions such as differentiation, proliferation, and apoptosis, as it relates to organogenesis, cancer, and wound healing
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